Methoxybenzoic acids and derivatives
Medchemexpress LLC Ro 08-2750 | 37854-59-4 | 98.01% | 270.24 | 10 MG
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor that binds to NGF with an IC50 of approximately 1 μM. It selectively inhibits NGF binding to p75NTR over TRKA. Ro 08-2750 is also a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM.
- Binds to the NGF dimer, potentially inducing a conformational change that prevents NGF from binding to p75NTR.
- Completely rescues cells from NGF-induced SK-N-MC 103 cell death at 10 nM.
- Increases differentiation and apoptosis in myeloid leukemia cells at 5-10 μM (8 hours).
- Inhibits survival of human AML lines and patient cells.
- Inhibits MSI2 RNA-binding and alters MSI2 gene signature.
- Inhibits leukemogenesis in a myeloid leukemia model in vivo at 13.75 mg/kg (i.p.).
- Reduces c-MYC levels and disease burden in a myeloid leukemia model.
Ambeed 6Aminobenzo c 1 2 oxaborol1 3
6-Aminobenzo[c][1,2]oxaborol-1(3H)-ol hydrochloride, 117098-93-8, 97%
Ambeed S 2 2 Bis diphenylphosphino
(S)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl, 139139-93-8, 98%
eMolecules 78191-00-1 | N-Methoxy-N-methylacetamide | Ochem Incorporation | MFCD00060098 | 103.121 | C4H9NO2 | 99.000 | CON(C)C(C)=O | 100g | 773131534
N-Methoxy-N-methylacetamide | Ochem Incorporation | 78191-00-1 | MFCD00060098 | 103.121 | C4H9NO2 | 99.000 | CON(C)C(C)=O | 100g | 773131534
Medchemexpress LLC Ethyl hydrogen malonate | 1071-46-1 | MFCD00020490 | ≥96.0% | 132.11 g/mol | C5H8O4 | 25g
3-Ethoxy-3-oxopropanoic acid is an endogenous metabolite 3-Ethoxy-3-oxopropanoic acid promotes plant growth[1]
eMolecules 2150-38-1 | Methyl 3,4-dimethoxybenzoate | Combi-Blocks | MFCD00008430 | 196.202 | C10H12O4 | 98.000 | COC(=O)c1ccc(OC)c(OC)c1 | 5g | 232308657
Methyl 3,4-dimethoxybenzoate | Combi-Blocks | 2150-38-1 | MFCD00008430 | 196.202 | C10H12O4 | 98.000 | COC(=O)c1ccc(OC)c(OC)c1 | 5g | 232308657
Apexbio Technology LLC 5-Methoxy-UTP 10ul (100 mM)
5-Methoxy-UTP is a modified uridine triphosphate nucleotide bearing a methoxy group at the carbon-5 position This modification significantly alters the chemical properties and biological functions of the nucleotide During in vitro mRNA synthesis 5-Methoxy-UTP can be incorporated into RNA molecules generating RNAs containing 5-methoxyuridine residues Methoxy-modified RNA plays an important role in studies focusing on RNA structure function and interactions with proteins Additionally 5-Methoxy-UTP markedly improves RNA stability and protects against intracellular degradation Therefore this modification is widely utilized in gene expression research RNA drug development and gene therapy applications
eMolecules 2150-38-1 | Methyl 3,4-dimethoxybenzoate | Combi-Blocks | MFCD00008430 | 196.202 | C10H12O4 | 98.000 | COC(=O)c1ccc(OC)c(OC)c1 | 25g | 290688130
Methyl 3,4-dimethoxybenzoate | Combi-Blocks | 2150-38-1 | MFCD00008430 | 196.202 | C10H12O4 | 98.000 | COC(=O)c1ccc(OC)c(OC)c1 | 25g | 290688130
Cambridge Isotope Laboratories 4-Methoxy-2 2 3 4 5 5-hexaCB (unlabeled) 50 ug/mL in nonane 1 2 mL
4-Methoxy-2 2 3 4 5 5-hexaCB (unlabeled) 50 ug/mL in nonane 1 2 mL
Aobchem 6-(Cyclopentyloxy)nicotinic acid | ≥97% | CAS 509101-14-8 | C11H13NO3 | 250mg
6-(Cyclopentyloxy)nicotinic acid | ≥97% | CAS 509101-14-8 | C11H13NO3 | 250mg
Aobchem 2-Formyl-3-methoxybenzoic acid | ≥95% | CAS 60407-04-7 | C9H8O4 | 250mg
2-Formyl-3-methoxybenzoic acid | ≥95% | CAS 60407-04-7 | C9H8O4 | 250mg